Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL10779022 | 0.93 | ALDH1A1 (0.40) | ALDH1A1TDP1CA2MMP1MMP2 | |
| SCHEMBL1923143 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TDP1CA2MMP1MMP2 | |
| SCHEMBL9579834 | 0.81 | GABRR1 (0.42) | TP53 | |
| SCHEMBL9127266 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TDP1CA2MMP1MMP2 | |
| SCHEMBL27687487 | 0.79 | TP53 (0.35) | ALDH1A1TDP1RNPEPSLC7A5TP53 | |
| SCHEMBL4576180 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TDP1CA2MMP1MMP2 | |
| SCHEMBL10592711 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TDP1CA2MMP1MMP2 | |
| SCHEMBL28931222 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TDP1CA2MMP1MMP2 | |
| SCHEMBL6942973 | 0.75 | GABRR1 (0.38) | SLC7A5LMNA | |
| SCHEMBL6692736 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10252291-B2 | Photo-curing of thermoplastic coatings | COLOPLAST A/S (DK) | 2019-04-09 | — | — | US | disclosed |
| CN-107459535-A | Polysubstituted quinoline coordinated iridium hybrid compound and preparation method and application thereof | 南京工业大学 | 2017-12-12 | — | — | CN | disclosed |
| EP-2049172-B1 | PHOTO-CURING OF THERMOPLASTIC COATINGS | COLOPLAST AS (DK) | 2014-12-31 | — | — | EP | disclosed |
| US-20140363562-A1 | PHOTO-CURING OF THERMOPLASTIC COATINGS | COLOPLAST A/S (DK) | 2014-12-11 | — | — | US | disclosed |
| US-20130289064-A1 | Salts and crystall forms of 2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile | NOVARTIS AG (CH) | 2013-10-31 | — | — | US | disclosed |
| US-20130115466-A1 | PHOTO-CURING OF THERMOPLASTIC COATINGS | COLOPLAST A/S (DK) | 2013-05-09 | — | — | US | disclosed |
| US-8436177-B2 | Salts and crystall forms of 2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile | NOVARTIS AG (CH) | 2013-05-07 | — | — | US | disclosed |
| EP-2364981-A1 | SALTS AND CRYSTALLINE FORMS OF 2-METHYL-2-[4- (3-METHYL-2-OXO-8-QUINOLIN-3-YL-2,3-DIHYDRO-IMIDAZO[4,5-C]QUINOLIN-1-YL)-PHENYL]-PROPIONITRILE | Novartis AG (CH) | 2011-09-14 | — | — | EP | disclosed |
| US-20100168153-A1 | Salts and crystall forms of 2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile | NOVARTIS AG (CH) | 2010-07-01 | — | — | US | disclosed |
| US-20100119833-A1 | PHOTO-CURING OF THERMOPLASTIC COATINGS | MADSEN NIELS JORGEN | 2010-05-13 | — | — | US | disclosed |
| EP-2094700-A2 | SALTS AND CRYSTALL FORMS OF 2-METHYL-2-[4-(3-METHYL-2-OXO-8-QUINOLIN-3-YL-2,3-DIHYDRO-IMIDAZO[4,5-C]QUINOLIN-1-YL)-PHENYL]-PROPIONITRILE | Novartis AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| EP-2049172-A2 | PHOTO-CURING OF THERMOPLASTIC COATINGS | Coloplast A/S (DK) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008064093-A2 | SALTS AND CRYSTAL FORMS OF 2-METHYL-2-[4-(3-METHYL-2-OXO-8-QUINOLIN-3-YL-2,3-DIHYDRO-IMIDAZO[4,5-C]QUINOLIN-1-YL)-PHENYL]-PROPIONITRILE | NOVARTIS AG (CH) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008012325-A2 | PHOTO-CURING OF THERMOPLASTIC COATINGS | COLOPLAST A/S (DK) | 2008-01-31 | — | — | WO | disclosed |
| US-4659728-A | ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130289064-A1 | Salts and crystall forms of 2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile | AQP3, MB, TTR | ALDH1A1 1652/4885TDP1 2183/4885CA2 63/4885 |
| US-20100168153-A1 | Salts and crystall forms of 2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile | AQP3, MB, TTR | ALDH1A1 1652/4885TDP1 2183/4885CA2 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.