Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26379449 | 0.85 | SIRT6 (0.40) | SIRT6SIRT1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL16384377 | 0.85 | CYP2D6 (0.45) | SIRT6SIRT1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL20414861 | 0.83 | KDM4E (0.52) | SIRT6SIRT1SIRT5DPP7GNAI3 | |
| SCHEMBL8106503 | 0.83 | KDM4E (0.52) | SIRT6SIRT1SIRT5DPP7GNAI3 | |
| SCHEMBL20411608 | 0.83 | KDM4E (0.52) | SIRT6SIRT1SIRT5DPP7GNAI3 | |
| SCHEMBL20411605 | 0.83 | KDM4E (0.52) | SIRT6SIRT1SIRT5DPP7GNAI3 | |
| SCHEMBL16283730 | 0.83 | NOD1 (0.50) | SIRT6SIRT1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14148761 | 0.81 | FNTA (0.48) | SIRT6SIRT1SIRT5DPP7GNAI3 | |
| SCHEMBL16283727 | 0.81 | TLR2 (0.45) | SIRT6SIRT1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19472246 | 0.81 | KDM4E (0.55) | SIRT6SIRT1SIRT5GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331801-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS | MEDIKINE, INC. (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230312653-A1 | CYCLIC CELL PENETRATING PEPTIDES | ENTRADA THERAPEUTICS, INC. | 2023-10-05 | — | — | US | disclosed |
| US-11718654-B2 | IL-2R-βγ binding compounds | MEDIKINE, INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-20220119493-A1 | IL-7R-ALPHA BINDING COMPOUNDS | SAMSARA BIOCAPITAL, L.P. | 2022-04-21 | — | — | US | disclosed |
| US-20220119492-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS AND USES THEREOF | JEFFREY W. AND CHRISTINA R. BIRD TRUST U/A/D | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331801-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS | IL2RA, IL2, IL15RA | SIRT6 4196/4885SIRT1 3438/4885CYP2D6 2614/4885 |
| US-20230312653-A1 | CYCLIC CELL PENETRATING PEPTIDES | SLC47A1, SLC47A2, VIP | SIRT6 3125/4885SIRT1 3781/4885CYP2D6 4762/4885 |
| US-11718654-B2 | IL-2R-βγ binding compounds | IL2RA, IL2, IL1RN | SIRT6 4125/4885SIRT1 3372/4885CYP2D6 3241/4885 |
| US-20220119492-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS AND USES THEREOF | IL2RA, IL2, IL15RA | SIRT6 4345/4885SIRT1 3643/4885CYP2D6 3475/4885 |
| US-20220119493-A1 | IL-7R-ALPHA BINDING COMPOUNDS | IL2RA, IL6ST, IL1RN | SIRT6 3038/4885SIRT1 3580/4885CYP2D6 2851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.