Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24308138 | 0.85 | SIRT6 (0.41) | SIRT6SIRT1SIRT5CYP2D6CYP2C9 | |
| SCHEMBL25944851 | 0.82 | SIRT6 (0.46) | SIRT6SIRT1SIRT5DPP7GNAI3 | |
| SCHEMBL27309897 | 0.81 | KISS1R (0.39) | SIRT6SIRT1SIRT5ALBEPHX1 | |
| SCHEMBL24958429 | 0.81 | KDM4E (0.35) | SIRT6SIRT1SIRT5ALBALDH1A1 | |
| SCHEMBL16283730 | 0.81 | NOD1 (0.50) | SIRT6SIRT1SIRT5CYP2D6CYP2C9 | |
| SCHEMBL22800728 | 0.81 | SIRT6 (0.35) | SIRT6SIRT1SIRT5DPP7GNAI3 | |
| SCHEMBL16283727 | 0.80 | TLR2 (0.45) | SIRT6SIRT1SIRT5CYP2D6CYP2C9 | |
| SCHEMBL24307799 | 0.79 | ALB (0.43) | SIRT6SIRT1SIRT5KMT2AALB | |
| SCHEMBL23589454 | 0.79 | SIRT6 (0.52) | SIRT6SIRT1DPP7GNAI3GNAO1 | |
| SCHEMBL25944734 | 0.79 | ALB (0.38) | SIRT6SIRT1SIRT5KMT2AALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312653-A1 | CYCLIC CELL PENETRATING PEPTIDES | ENTRADA THERAPEUTICS, INC. | 2023-10-05 | — | — | US | disclosed |
| US-20230312653-A1 | CYCLIC CELL PENETRATING PEPTIDES | ENTRADA THERAPEUTICS, INC. | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312653-A1 | CYCLIC CELL PENETRATING PEPTIDES | SLC47A1, SLC47A2, VIP | SIRT6 3125/4885SIRT1 3781/4885SIRT5 4261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.