Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24309539 | 0.92 | TACR1 (0.32) | TACR1 | |
| SCHEMBL24310722 | 0.87 | AXL (0.30) | AXL | |
| SCHEMBL24310085 | 0.87 | CDK1 (0.30) | — | |
| SCHEMBL24310404 | 0.86 | TACR1 (0.33) | TACR1AXL | |
| SCHEMBL29566949 | 0.85 | HTR1A (0.34) | TACR1 | |
| SCHEMBL24310520 | 0.85 | HTR1A (0.34) | TACR1 | |
| SCHEMBL24310455 | 0.84 | DRD2 (0.31) | AXL | |
| SCHEMBL24310712 | 0.84 | AXL (0.33) | AXL | |
| SCHEMBL24310558 | 0.84 | IGF1R (0.31) | TACR1 | |
| SCHEMBL24310709 | 0.82 | DRD2 (0.33) | AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |