Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24310523 | 0.87 | TACR1 (0.31) | AXL | |
| SCHEMBL24310734 | 0.87 | — | — | |
| SCHEMBL24309719 | 0.86 | MAP4K1 (0.37) | MAP4K1 | |
| SCHEMBL24310712 | 0.85 | AXL (0.33) | AXL | |
| SCHEMBL29566574 | 0.84 | HTR1A (0.34) | — | |
| SCHEMBL26808972 | 0.84 | HTR1A (0.34) | — | |
| SCHEMBL24310709 | 0.82 | DRD2 (0.33) | AXLMAP4K1 | |
| SCHEMBL24310404 | 0.81 | TACR1 (0.33) | AXL | |
| SCHEMBL24309882 | 0.80 | MAP4K1 (0.37) | MAP4K1 | |
| SCHEMBL24310428 | 0.80 | MAP4K1 (0.38) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |