Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 5/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 5/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24312045 | 0.87 | MAP3K5 (0.45) | PRMT5WDR77ABHD6PTGDR2MAP3K5 | |
| SCHEMBL15355424 | 0.81 | PRMT5 (0.67) | PRMT5WDR77ABHD6 | |
| SCHEMBL1857142 | 0.79 | UCHL1 (0.53) | ABHD6 | |
| SCHEMBL30647075 | 0.79 | UCHL1 (0.53) | ABHD6 | |
| SCHEMBL1201971 | 0.71 | PRMT5 (0.48) | PRMT5WDR77TMEM97SIGMAR1ABHD6 | |
| SCHEMBL28486528 | 0.70 | RAB9A (0.44) | PRMT5WDR77PTGDR2PPARGPPARA | |
| SCHEMBL29801280 | 0.70 | ESR2 (0.54) | PRMT5WDR77TMEM97SIGMAR1ABHD6 | |
| SCHEMBL1570606 | 0.70 | ESR2 (0.54) | PRMT5WDR77TMEM97SIGMAR1ABHD6 | |
| SCHEMBL21807308 | 0.70 | UCHL1 (0.54) | ABHD6 | |
| SCHEMBL30404761 | 0.69 | TMEM97 (0.47) | PRMT5WDR77TMEM97SIGMAR1ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220105194-A1 | CONJUGATE COMPRISING LIGAND, SPACER, PEPTIDE LINKER, AND BIOMOLECULE | ASTELLAS PHARMA INC. (JP) | 2022-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220105194-A1 | CONJUGATE COMPRISING LIGAND, SPACER, PEPTIDE LINKER, AND BIOMOLECULE | MUC1, CA14, CA13 | PRMT5 2013/4885WDR77 1997/4885TMEM97 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.