Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 5/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25734114 | 1.00 | DNM1 (0.49) | DNM1ALDH1A1TSHRTHRATHRB | |
| SCHEMBL25629223 | 0.92 | DNM1 (0.51) | DNM1ALDH1A1TSHRTHRATHRB | |
| SCHEMBL22072274 | 0.85 | ALDH1A1 (0.44) | DNM1ALDH1A1TSHRTHRATHRB | |
| SCHEMBL22448848 | 0.84 | DNM1 (0.47) | DNM1ALDH1A1THRATHRBKDM4E | |
| SCHEMBL23791993 | 0.84 | DNM1 (0.65) | DNM1THRATHRBCASP2PAOX | |
| SCHEMBL19823328 | 0.82 | TDP1 (0.44) | DNM1ALDH1A1TSHRTHRATHRB | |
| SCHEMBL24507280 | 0.82 | CASP2 (0.57) | ALDH1A1TSHRCASP2EPHX1 | |
| SCHEMBL22838207 | 0.82 | CASP2 (0.57) | ALDH1A1TSHRCASP2EPHX1 | |
| SCHEMBL24982530 | 0.82 | CASP2 (0.57) | ALDH1A1TSHRCASP2EPHX1 | |
| SCHEMBL19578063 | 0.82 | CASP2 (0.57) | ALDH1A1TSHRCASP2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3960242-A1 | CONJUGATE AND CANCER THERAPEUTIC AGENT | Tokyo Institute of Technology (JP) | 2022-03-02 | — | — | EP | disclosed |