Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313491 | 0.84 | PIK3CD (0.36) | PIK3CDMEN1KMT2A | |
| SCHEMBL21516843 | 0.82 | PIK3CD (0.57) | PIK3CDMEN1KMT2AHMGCRCHRM1 | |
| SCHEMBL20904149 | 0.78 | PIK3CD (0.32) | PIK3CD | |
| SCHEMBL25982395 | 0.71 | METAP2 (0.32) | — | |
| SCHEMBL17199436 | 0.70 | PIK3CD (0.53) | PIK3CDMEN1KMT2AHMGCRCHRM1 | |
| SCHEMBL31445676 | 0.69 | PIK3CD (0.44) | PIK3CDHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL4282052 | 0.69 | — | — | |
| SCHEMBL158577 | 0.69 | — | — | |
| SCHEMBL24259748 | 0.68 | MME (0.33) | — | |
| SCHEMBL21536797 | 0.67 | FAAH (0.46) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784666-B1 | ANTIPROLIFERATION COMPOUNDS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2022-03-16 | — | — | EP | disclosed |