Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313100 | 0.84 | PIK3CD (0.53) | PIK3CDMEN1KMT2A | |
| SCHEMBL22280301 | 0.83 | PIK3CD (0.40) | PIK3CDSMN1; SMN2HTTHPGDMEN1 | |
| SCHEMBL7890623 | 0.81 | MEN1 (0.43) | PIK3CDSMN1; SMN2HTTHPGDMEN1 | |
| SCHEMBL20904149 | 0.79 | PIK3CD (0.32) | PIK3CD | |
| SCHEMBL26662231 | 0.77 | PIK3CD (0.36) | PIK3CDSMN1; SMN2HTTHPGDMEN1 | |
| SCHEMBL22820158 | 0.76 | CNR2 (0.39) | PIK3CDSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL6359867 | 0.76 | MMP1 (0.45) | SMN1; SMN2HTTHPGDMEN1KMT2A | |
| SCHEMBL13079648 | 0.76 | SMN1; SMN2 (0.38) | PIK3CDSMN1; SMN2HTTHPGDMEN1 | |
| SCHEMBL19020334 | 0.75 | HPGD (0.34) | SMN1; SMN2HTTHPGDMEN1KMT2A | |
| SCHEMBL18363115 | 0.74 | HPGD (0.40) | PIK3CDSMN1; SMN2HTTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784666-B1 | ANTIPROLIFERATION COMPOUNDS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2022-03-16 | — | — | EP | disclosed |