Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 8/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24261276 | 0.80 | FAAH (0.36) | FAAHGPR84KDM4ELMNAUSP2 | |
| SCHEMBL23082844 | 0.80 | FAAH (0.36) | FAAHGPR84KDM4ELMNAUSP2 | |
| SCHEMBL19578799 | 0.79 | PPARG (0.38) | FAAHPPARG | |
| SCHEMBL21755112 | 0.79 | ADA (0.42) | ALDH1A1FAAHTLR8KDM4EALOX15 | |
| SCHEMBL25452695 | 0.77 | PTPN1 (0.42) | ALDH1A1L3MBTL1FAAHPPARGKDM4E | |
| SCHEMBL30541526 | 0.77 | ADA (0.40) | FAAHTLR8 | |
| SCHEMBL27834249 | 0.77 | ADA (0.40) | FAAHTLR8 | |
| SCHEMBL29117493 | 0.76 | FAAH (0.39) | ALDH1A1FAAHTLR8PPARGDAGLA | |
| SCHEMBL2084128 | 0.76 | L3MBTL1 (0.53) | ALDH1A1L3MBTL1FAAHKDM4ELMNA | |
| SCHEMBL21776261 | 0.75 | LMNA (0.36) | FAAHTLR8PPARGGPR84KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4043460-A1 | ANTIPROLIFERATION COMPOUNDS AND USES THEREOF | Merck Patent GmbH (DE) | 2022-08-17 | — | — | EP | disclosed |
| EP-3784666-B1 | ANTIPROLIFERATION COMPOUNDS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2022-03-16 | — | — | EP | disclosed |