Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910636 | 0.94 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL31741320 | 0.83 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL3625534 | 0.82 | KDM4E (0.57) | NPC1RAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL6361482 | 0.81 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2LMNAGAA | |
| 2-Nonanone SCHEMBL19665201 | 0.81 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL11763977 | 0.80 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL1397437 | 0.80 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL11796309 | 0.78 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL3024111 | 0.78 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL6675357 | 0.78 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011111460-A1 | POLYMER SUPPORTED BORON CATALYST AND METHOD FOR PRODUCING MICHAEL ADDITION REACTION PRODUCT USING THAT CATALYST | 独立行政法人科学技術振興機構 (JP) | 2011-09-15 | — | — | WO | disclosed |