Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | FADS1 | O60427 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.51 |
| ▸ | PLAT | P00750 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSH | P09668 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793295 | 0.96 | LMNA (0.58) | LMNAEPHX2MEN1KMT2ANPC1 | |
| SCHEMBL3477718 | 0.94 | EPHX2 (0.60) | LMNAEPHX2MEN1KMT2ANPC1 | |
| SCHEMBL4176467 | 0.92 | FADS1 (0.54) | LMNAEPHX2MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL16345623 | 0.90 | FADS1 (0.53) | LMNAEPHX2MEN1KMT2ANPC1 | |
| SCHEMBL4139369 | 0.84 | HTR6 (0.56) | LMNAEPHX2MEN1KMT2ANPC1 | |
| SCHEMBL2094908 | 0.84 | FADS1 (0.48) | LMNAEPHX2MEN1KMT2ANPC1 | |
| SCHEMBL7794546 | 0.84 | PIM1 (0.48) | LMNAEPHX2MEN1KMT2ANPC1 | |
| SCHEMBL1496158 | 0.82 | IDH2 (0.48) | LMNAEPHX2MEN1KMT2ANPC1 | |
| SCHEMBL911849 | 0.82 | SLC6A4 (0.46) | LMNAEPHX2MEN1KMT2ANPC1 | |
| SCHEMBL12903150 | 0.82 | SLC6A4 (0.46) | LMNAEPHX2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4043460-A1 | ANTIPROLIFERATION COMPOUNDS AND USES THEREOF | Merck Patent GmbH (DE) | 2022-08-17 | — | — | EP | disclosed |
| EP-3784666-B1 | ANTIPROLIFERATION COMPOUNDS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2022-03-16 | — | — | EP | disclosed |