SCHEMBL2434428

SCHEMBL2434428

CCC(C)(C)c1ccc2c(c1)[PH](=O)Oc1ccccc1-2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
CASP3 P42574 2/20 0.51
SENP8 Q96LD8 2/20 0.51
SENP7 Q9BQF6 2/20 0.51
SENP6 Q9GZR1 2/20 0.51
LMNA P02545 1/20 0.51
MAPK1 P28482 1/20 0.51
ATM Q13315 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ALDH1A1 P00352 1/20 0.33
PLA2G1B P04054 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
CNR1 P21554 2/20 0.32
CNR2 P34972 2/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2436801 0.88 NPC1 (0.38) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL2434135 0.86 NPC1 (0.51) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL2436802 0.86 CNR1 (0.48) CNR1CNR2
SCHEMBL2435405 0.86 ALDH1A1 (0.46) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL2428112 0.77 MAPT (0.46) NPC1RAB9ALMNAMAPK1SMN1; SMN2
SCHEMBL2431336 0.76 MAPK1 (0.43) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL2438109 0.75 ELANE (0.42) LMNA
SCHEMBL2434393 0.75 ALDH1A1 (0.39) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL2431660 0.75 NPC1 (0.38) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL9490986 0.74 ALDH1A1 (0.46) NPC1RAB9ACASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed