Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24513936 | 0.89 | KDM4E (0.33) | ARG1ARG2MEN1FAAHMAPK1 | |
| SCHEMBL22794331 | 0.85 | MAPK1 (0.37) | ARG1ARG2MEN1FAAHMAPK1 | |
| SCHEMBL25479251 | 0.85 | MAPK1 (0.37) | ARG1ARG2MEN1FAAHMAPK1 | |
| SCHEMBL20099422 | 0.80 | ARG1 (0.33) | ARG1ARG2MEN1FAAHMAPK1 | |
| SCHEMBL20046942 | 0.78 | KDM4E (0.36) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL20825683 | 0.74 | KMT2A (0.43) | MEN1MAPK1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL2179403 | 0.73 | — | — | |
| SCHEMBL7357585 | 0.73 | — | — | |
| SCHEMBL13282148 | 0.73 | — | — | |
| SCHEMBL20734550 | 0.71 | ALDH1A1 (0.46) | ARG1ARG2KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053650-A1 | THERAPEUTIC B7-H4 BINDING MOLECULES | MEDIMMUNE LIMITED (GB) | 2022-03-17 | — | — | WO | disclosed |