Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23975222 | 0.83 | MMP1 (0.42) | MMP1MMP2MMP3CA12CA1 | |
| SCHEMBL22820158 | 0.83 | CNR2 (0.39) | SMN1; SMN2HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL22280301 | 0.81 | PIK3CD (0.40) | CA1CA2SMN1; SMN2GAAHTT | |
| SCHEMBL14241693 | 0.81 | SMN1; SMN2 (0.44) | MMP1MMP2MMP3CA12CA1 | |
| SCHEMBL19200100 | 0.81 | SMN1; SMN2 (0.44) | MMP1MMP2MMP3CA12CA1 | |
| SCHEMBL13253317 | 0.81 | MLYCD (0.40) | MMP1MMP2MMP3SMN1; SMN2HTT | |
| SCHEMBL7890623 | 0.79 | MEN1 (0.43) | MMP1MMP2CA12CA1CA2 | |
| SCHEMBL18946428 | 0.79 | SMN1; SMN2 (0.46) | MMP1MMP2MMP3CA12CA1 | |
| SCHEMBL16730101 | 0.78 | LMNA (0.41) | SMN1; SMN2HTTL3MBTL1KDM4EKMT2A | |
| SCHEMBL21307515 | 0.77 | POLB (0.37) | CA1CA2SMN1; SMN2PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3497094-B1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2023-02-15 | — | — | EP | disclosed |
| US-8168654-B2 | Quinuclidine derivatives binding to mucarinic M3 receptors | NOVARTIS AG (CH) | 2012-05-01 | — | — | US | disclosed |