Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 9/20 | 0.58 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.58 |
| ▸ | METTL3 | Q86U44 | 15/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29610953 | 1.00 | PRMT5 (0.58) | PRMT5WDR77METTL3 | |
| SCHEMBL27091940 | 0.95 | METTL3 (0.56) | PRMT5WDR77METTL3 | |
| SCHEMBL27090407 | 0.95 | METTL3 (0.56) | PRMT5WDR77METTL3 | |
| SCHEMBL29611585 | 0.89 | METTL3 (0.49) | PRMT5WDR77METTL3 | |
| SCHEMBL30642209 | 0.89 | METTL3 (0.49) | PRMT5WDR77METTL3 | |
| SCHEMBL29610961 | 0.88 | METTL3 (0.48) | PRMT5WDR77METTL3 | |
| SCHEMBL24313506 | 0.88 | METTL3 (0.48) | PRMT5WDR77METTL3 | |
| SCHEMBL29610846 | 0.88 | METTL3 (0.48) | PRMT5WDR77METTL3 | |
| SCHEMBL29611820 | 0.88 | METTL3 (0.61) | PRMT5WDR77METTL3 | |
| SCHEMBL29611379 | 0.88 | METTL3 (0.47) | PRMT5WDR77METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240051985-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS INC (US) | 2024-02-15 | — | — | US | disclosed |
| CN-117098767-A | METTL3 modulators | 埃克森特治疗公司 | 2023-11-21 | — | — | CN | disclosed |
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240051985-A1 | METTL3 MODULATORS | METTL3, METTL16, METTL14 | PRMT5 78/4885WDR77 119/4885METTL3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.