Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 13/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313682 | 0.91 | ALDH1A1 (0.34) | KCNH2MCHR1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL24314223 | 0.90 | PDE4A (0.34) | KCNH2MCHR1CNR2 | |
| SCHEMBL24313763 | 0.89 | KCNH2 (0.39) | KCNH2MCHR1CNR2ALDH1A1POLB | |
| SCHEMBL24314317 | 0.89 | PDK2 (0.37) | — | |
| SCHEMBL24314313 | 0.88 | ACACB (0.36) | — | |
| SCHEMBL24314217 | 0.86 | PDE4D (0.31) | — | |
| SCHEMBL24314303 | 0.85 | MEN1 (0.35) | KCNH2MCHR1ALDH1A1POLBCYP1A2 | |
| SCHEMBL24313977 | 0.83 | CYP1A2 (0.37) | KCNH2MCHR1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL24313683 | 0.82 | KCNH2 (0.40) | KCNH2MCHR1CNR2ALDH1A1CACNA1G | |
| SCHEMBL24314235 | 0.81 | KCNH2 (0.36) | KCNH2MCHR1ALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |