Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 15/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313686 | 0.91 | ALDH1A1 (0.44) | KCNH2MCHR1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29588648 | 0.90 | SCN9A (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL24314222 | 0.90 | SCN9A (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL29587334 | 0.89 | KCNH2 (0.39) | KCNH2MCHR1CNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL29588713 | 0.88 | MMP2 (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24314311 | 0.88 | MMP2 (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29587518 | 0.87 | ACACB (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24314316 | 0.87 | ACACB (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24314300 | 0.86 | ALDH1A1 (0.38) | KCNH2MCHR1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL24314216 | 0.86 | SCN9A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229045-B1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | BROAD INST INC (US) | 2025-11-12 | — | — | EP | claimed |
| EP-4229045-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute Inc. (US) | 2023-08-23 | — | — | EP | claimed |
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | claimed |
| EP-4229045-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |