Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313961 | 0.88 | CTSD (0.33) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL24313682 | 0.88 | ALDH1A1 (0.34) | — | |
| SCHEMBL24314223 | 0.87 | PDE4A (0.34) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL24313680 | 0.86 | KCNH2 (0.39) | — | |
| SCHEMBL24314317 | 0.85 | PDK2 (0.37) | — | |
| SCHEMBL24314313 | 0.85 | ACACB (0.36) | — | |
| SCHEMBL24313698 | 0.85 | SCN9A (0.33) | — | |
| SCHEMBL24313750 | 0.83 | KAT2B (0.33) | — | |
| SCHEMBL24314303 | 0.82 | MEN1 (0.35) | — | |
| SCHEMBL29587379 | 0.82 | SCN9A (0.35) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |