Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29587472 | 1.00 | ERN1 (0.36) | ERN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24313733 | 0.84 | DRD1 (0.34) | PDE4APDE4BPDE4CPDE4DDRD1 | |
| SCHEMBL28233128 | 0.75 | ERN1 (0.40) | ERN1DRD1CA12CA1CA2 | |
| SCHEMBL24313611 | 0.74 | ESR2 (0.36) | ERN1ESR2 | |
| SCHEMBL12174452 | 0.73 | HDAC4 (0.42) | ERN1ESR2 | |
| SCHEMBL24313735 | 0.71 | HTR2A (0.35) | ESR2KDM4E | |
| SCHEMBL29587536 | 0.71 | ESR2 (0.34) | ERN1ESR2 | |
| SCHEMBL29588792 | 0.71 | HTR2A (0.35) | ESR2KDM4E | |
| SCHEMBL24314202 | 0.71 | ESR2 (0.34) | ERN1ESR2 | |
| SCHEMBL22093032 | 0.68 | PDE4D (0.34) | PDE4APDE4BPDE4CPDE4DMAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229045-B1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | BROAD INST INC (US) | 2025-11-12 | — | — | EP | disclosed |
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |