Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24314187 | 0.91 | MCHR1 (0.36) | MCHR1KCNH2ACHEKMT2ACACNA1B | |
| SCHEMBL24313811 | 0.90 | MCHR1 (0.38) | MCHR1KCNH2ACHEABCB1CCR5 | |
| SCHEMBL24333743 | 0.88 | MCHR1 (0.38) | MCHR1KCNH2ACHEABCB1CCR5 | |
| SCHEMBL24314235 | 0.84 | KCNH2 (0.36) | MCHR1KCNH2KMT2A | |
| SCHEMBL24313761 | 0.83 | MEN1 (0.32) | MCHR1KCNH2KMT2A | |
| SCHEMBL24313698 | 0.83 | SCN9A (0.33) | — | |
| SCHEMBL24313754 | 0.81 | MEN1 (0.36) | KCNH2CCR5KMT2A | |
| SCHEMBL24313750 | 0.81 | KAT2B (0.33) | MCHR1KCNH2 | |
| SCHEMBL24314319 | 0.80 | CNR2 (0.33) | MCHR1KCNH2 | |
| SCHEMBL24313634 | 0.79 | RAB9A (0.34) | MCHR1KCNH2ACHEKMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |