Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | IL2 | P60568 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313801 | 0.87 | RAB9A (0.36) | RAB9AALDH1A1NPC1KDM4EHTT | |
| SCHEMBL24313727 | 0.86 | MAPK1 (0.33) | RAB9AALDH1A1NPC1KDM4EHTT | |
| SCHEMBL24313756 | 0.85 | LMNA (0.33) | RAB9AALDH1A1NPC1KDM4EHTT | |
| SCHEMBL24313907 | 0.84 | PDE2A (0.34) | RAB9AALDH1A1NPC1KDM4EHTT | |
| SCHEMBL24313750 | 0.83 | KAT2B (0.33) | RAB9AALDH1A1NPC1KDM4EHTT | |
| SCHEMBL24314319 | 0.82 | CNR2 (0.33) | RAB9ANPC1MCHR1KCNH2USP5 | |
| SCHEMBL24313754 | 0.81 | MEN1 (0.36) | ALDH1A1KDM4EHTTHPGDSMN1; SMN2 | |
| SCHEMBL24313775 | 0.79 | MCHR1 (0.38) | MCHR1KCNH2MAOBALOX5MAOA | |
| SCHEMBL24313633 | 0.77 | HPGD (0.44) | KDM4EHPGDLMNAKMT2A | |
| SCHEMBL24314181 | 0.76 | MCL1 (0.41) | ALDH1A1KDM4EHTTHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |