Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 5/20 | 0.41 |
| ▸ | TYMP | P19971 | 2/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29610840 | 1.00 | METTL3 (0.41) | METTL3TYMPADKCYP1A2CYP3A4 | |
| SCHEMBL24313851 | 0.90 | METTL3 (0.34) | METTL3CYP1A2CYP3A4CYP2C9CLK4 | |
| SCHEMBL29610880 | 0.90 | METTL3 (0.34) | METTL3CYP1A2CYP3A4CYP2C9CLK4 | |
| SCHEMBL29610890 | 0.89 | METTL3 (0.44) | METTL3ADKCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24313840 | 0.89 | METTL3 (0.44) | METTL3ADKCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30642250 | 0.85 | CYP1A2 (0.35) | TYMPCYP1A2CYP3A4CYP2C9CLK4 | |
| SCHEMBL24313843 | 0.81 | METTL3 (0.38) | METTL3ADKCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27090405 | 0.81 | METTL3 (0.38) | METTL3ADKCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24313850 | 0.75 | PRMT5 (0.47) | METTL3ADKCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29611468 | 0.75 | PRMT5 (0.47) | METTL3ADKCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240051985-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS INC (US) | 2024-02-15 | — | — | US | disclosed |
| EP-4229067-A1 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240051985-A1 | METTL3 MODULATORS | METTL3, METTL16, METTL14 | METTL3 1/4885TYMP 881/4885ADK 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.