SCHEMBL2431396

SCHEMBL2431396

CC(C)(C)c1cc2c(c(C3CCCCC3)c1)O[PH](=O)c1ccccc1-2

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.33
PTPN5 P54829 3/20 0.32
PTPN2 P17706 1/20 0.32
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PLA2G1B P04054 1/20 0.31
NFKB1 P19838 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2431986 0.83 PTGS2 (0.33) PTGS2PTPN5PTPN2
SCHEMBL30165040 0.83 PTGS2 (0.33) PTGS2PTPN5PTPN2
SCHEMBL30594716 0.80 PTGS2 (0.39) PTGS2PTPN5PTPN2CASP3SENP7
SCHEMBL2433451 0.80 PTGS2 (0.39) PTGS2PTPN5PTPN2CASP3SENP7
SCHEMBL2441507 0.79 PDK2 (0.32)
SCHEMBL2433974 0.79 NPC1 (0.38) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL2434834 0.78 PTGDR2 (0.31) PTGS2
SCHEMBL2430321 0.77 NPC1 (0.37) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL30594719 0.77 NPC1 (0.37) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL2427175 0.73 PTPN5 (0.33) PTGS2PTPN5PTPN2NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed