SCHEMBL2433974

SCHEMBL2433974

Cc1cc(C(C)(C)C)cc2c1O[PH](=O)c1ccccc1-2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.38
CASP3 P42574 2/20 0.38
RAB9A P51151 2/20 0.38
SENP8 Q96LD8 2/20 0.38
SENP7 Q9BQF6 2/20 0.38
SENP6 Q9GZR1 2/20 0.38
ALDH1A1 P00352 1/20 0.38
PLA2G1B P04054 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
ATM Q13315 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HTR1D P28221 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30594719 0.87 NPC1 (0.37) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL2430321 0.87 NPC1 (0.37) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL2431409 0.83 ELANE (0.33) ALDH1A1L3MBTL1LMNAMAPK1SMN1; SMN2
SCHEMBL2437141 0.83 NPC1 (0.33) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL2431396 0.79 PTGS2 (0.33) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL2430825 0.78 MYC (0.33) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL30165037 0.78 MYC (0.33) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL2438498 0.78 ALDH1A1 (0.46) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL2435285 0.77 PTPN1 (0.37) NPC1RAB9AALDH1A1L3MBTL1LMNA
SCHEMBL2434927 0.77 MAPK1 (0.43) NPC1CASP3RAB9ASENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed