Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23273892 | 0.91 | ADORA3 (0.44) | ADORA3ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL24314224 | 0.88 | ADORA3 (0.43) | ADORA3ADORA2AUSP2ALDH1A1CYP1A2 | |
| SCHEMBL23312996 | 0.88 | ADORA3 (0.42) | ADORA3ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9109338 | 0.86 | ADORA3 (0.46) | ADORA3ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL23273891 | 0.85 | ADORA3 (0.40) | ADORA3ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL24313539 | 0.80 | CYP1A2 (0.36) | ADORA3ADORA2AADORA1USP2ALDH1A1 | |
| SCHEMBL24313864 | 0.79 | ADORA3 (0.43) | ADORA3USP2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL24313565 | 0.79 | ADORA3 (0.43) | ADORA3ADORA2AUSP2ALDH1A1CYP1A2 | |
| SCHEMBL29611653 | 0.79 | ADORA3 (0.43) | ADORA3ADORA2AUSP2ALDH1A1CYP1A2 | |
| SCHEMBL29610857 | 0.79 | ADORA3 (0.43) | ADORA3USP2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |