Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23273892 | 0.88 | ADORA3 (0.44) | ADORA3ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL24314227 | 0.88 | ADORA3 (0.44) | ADORA3ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL29772282 | 0.87 | RXFP1 (0.37) | ADORA3ADORA2AADORA1METTL3PRMT5 | |
| SCHEMBL23273891 | 0.85 | ADORA3 (0.40) | ADORA3ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL29611642 | 0.84 | METTL3 (0.49) | ADORA3METTL3PRMT5 | |
| SCHEMBL24313846 | 0.84 | METTL3 (0.49) | ADORA3METTL3PRMT5 | |
| SCHEMBL9109338 | 0.83 | ADORA3 (0.46) | ADORA3ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL24313539 | 0.81 | CYP1A2 (0.36) | ADORA3ADORA2AADORA1 | |
| SCHEMBL23273756 | 0.77 | METTL3 (0.46) | ADORA3ADORA2AADORA1METTL3PRMT5 | |
| SCHEMBL29772301 | 0.77 | METTL3 (0.46) | ADORA3ADORA2AADORA1METTL3PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298179-A | METTL3 modulators | 埃克森特治疗公司 | 2022-11-04 | — | — | CN | disclosed |
| EP-4048674-A2 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2022-08-31 | — | — | EP | disclosed |
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2021079196-A2 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2021-04-29 | — | — | WO | disclosed |