Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 9/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | TSHR | P16473 | 7/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.36 |
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23273892 | 0.88 | ADORA3 (0.44) | CYP1A2CYP3A4CYP2C19ADORA3ALDH1A1 | |
| SCHEMBL29610857 | 0.83 | ADORA3 (0.43) | CYP1A2CYP3A4CYP2C19ADORA3ALDH1A1 | |
| SCHEMBL29611653 | 0.83 | ADORA3 (0.43) | CYP1A2CYP3A4CYP2C19ADORA3ALDH1A1 | |
| SCHEMBL24313864 | 0.83 | ADORA3 (0.43) | CYP1A2CYP3A4CYP2C19ADORA3ALDH1A1 | |
| SCHEMBL24313565 | 0.83 | ADORA3 (0.43) | CYP1A2CYP3A4CYP2C19ADORA3ALDH1A1 | |
| SCHEMBL23312996 | 0.81 | ADORA3 (0.42) | ADORA3ADORA2AADORA1 | |
| SCHEMBL24314227 | 0.80 | ADORA3 (0.44) | CYP1A2CYP3A4CYP2C19ADORA3ALDH1A1 | |
| SCHEMBL24313535 | 0.79 | ADORA3 (0.40) | ADORA3 | |
| SCHEMBL29610818 | 0.79 | ADORA3 (0.40) | ADORA3 | |
| SCHEMBL29772282 | 0.79 | RXFP1 (0.37) | CYP1A2CYP3A4CYP2C19ADORA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |