Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15070924 | 0.83 | ESR1 (0.53) | ESR1ESR2TP53TDP1AR | |
| SCHEMBL4378266 | 0.83 | XDH (0.44) | ESR1ESR2ARXDHALDH1A1 | |
| SCHEMBL6373228 | 0.82 | ESR1 (0.57) | ESR1ESR2TP53TDP1AR | |
| SCHEMBL219534 | 0.82 | XDH (0.68) | ESR1ESR2TP53TDP1AR | |
| SCHEMBL28215864 | 0.82 | XDH (0.68) | ESR1ESR2TP53TDP1AR | |
| SCHEMBL2560484 | 0.80 | ALDH1A1 (0.37) | ESR1ESR2TDP1ALDH1A1MEN1 | |
| SCHEMBL29929036 | 0.80 | XDH (0.65) | ESR1TP53TDP1ARXDH | |
| SCHEMBL891837 | 0.80 | XDH (0.65) | ESR1TP53TDP1ARXDH | |
| SCHEMBL10907860 | 0.80 | ESR1 (0.59) | ESR1ESR2TP53TDP1AR | |
| SCHEMBL8852877 | 0.80 | ESR1 (0.59) | ESR1ESR2TP53TDP1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777641-B | Phosphorus-containing compound, epoxy resin composition, molding compound product, preparation method and application | 中国科学院宁波材料技术与工程研究所 | 2020-12-11 | — | — | CN | disclosed |
| CN-111777641-A | Phosphorus-containing compound, epoxy resin composition, molding compound product, preparation method and application | 中国科学院宁波材料技术与工程研究所 | 2020-10-16 | — | — | CN | disclosed |
| US-9493436-B2 | Tyrosine phosphatase inhibitors and uses thereof to modulate the activity of enzymes involved in the pathology of Mycobacterium tuberculosis | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-11-15 | — | — | US | disclosed |
| EP-3041822-A1 | COMPOUNDS USEFUL AS IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2016-07-13 | — | — | EP | disclosed |
| EP-3024825-A1 | IMIDAZOLECARBOXAMIDES AND THEIR USE AS FAAH INHIBITORS | Bial-Portela & CA, S.A. (PT) | 2016-06-01 | — | — | EP | disclosed |
| US-9314023-B2 | Tetrazolinone compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-04-19 | — | — | US | disclosed |
| WO-2015034820-A1 | COMPOUNDS USEFUL AS IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-03-12 | — | — | WO | disclosed |
| WO-2015012708-A1 | IMIDAZOLECARBOXAMIDES AND THEIR USE AS FAAH INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2015-01-29 | — | — | WO | disclosed |
| EP-2582674-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | Metabolex Inc. (US) | 2013-04-24 | — | — | EP | disclosed |
| EP-2579717-A2 | POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 | Merck Sharp & Dohme Corp. (US) | 2013-04-17 | — | — | EP | disclosed |
| EP-2029507-A1 | PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES | High Point Pharmaceuticals, LLC (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-1948617-A2 | PYRIMIDINONES AS CASEIN KINASE II (CK2) MODULATORS | Exelixis, Inc. (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007141295-A1 | PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES | HIGH POINT PHARMACEUTICALS, LLC (US) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007048065-A2 | PYRIMIDINONES AS CASEIN KINASE II (CK2) MODULATORS | EXELIXIS, INC. (US) | 2007-04-26 | — | — | WO | disclosed |
| EP-1673366-A1 | 1-\"2-(4-HYDROXYPHENYL)-2-HYDROXYETHYL]-PIPERIDIN-4-OL COMPOUNDS AS NMDA RECEPTOR ANTAGONISTS | Pfizer, Inc. (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005035522-A1 | 1-‘2-(4-HYDROXYPHENYL)-2-HYDROXYETHYL!-PIPERIDIN-4-OL COMPOUNDS AS NMDA RECEPTOR ANTAGONISTS | PFIZER JAPAN, INC. (JP) | 2005-04-21 | — | — | WO | disclosed |
| WO-2003105850-A1 | 2-AMINOQUINOLINES AS MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2003-12-24 | — | — | WO | disclosed |
| EP-1086097-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER INC. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064415-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 1999-12-16 | — | — | WO | disclosed |
| EP-0156734-A2 | Triazolo[4,3-b]pyridazines, process for their preparation and pharmaceutical compositions containing them | SANOFI S.A. (FR) | 1985-10-02 | — | — | EP | disclosed |