SCHEMBL891837

SCHEMBL891837

O=CCc1ccc(O)c(O)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.65
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA4 P22748 1/20 0.58
CA6 P23280 1/20 0.58
ALOX15 P16050 5/20 0.54
IGF1R P08069 2/20 0.54
TRPA1 O75762 2/20 0.54
KDM4E B2RXH2 7/20 0.54
MAPT P10636 6/20 0.54
HIF1A Q16665 4/20 0.54
HSD17B10 Q99714 4/20 0.54
TDP1 Q9NUW8 4/20 0.54
GAA P10253 3/20 0.54
THPO P40225 3/20 0.54
LMNA P02545 3/20 0.54
HPGD P15428 3/20 0.54
BLM P54132 3/20 0.54
PMP22 Q01453 3/20 0.54
APEX1 P27695 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29929036 1.00 XDH (0.65) XDHCA1CA2CA4CA6
SCHEMBL15173164 0.86 XDH (0.48) XDHCA1CA2CA4CA6
SCHEMBL26249726 0.83 XDH (0.68) XDHCA1CA2CA4CA6
SCHEMBL4378266 0.80 XDH (0.44) XDHCA1CA2CA4CA6
SCHEMBL4767670 0.80 CA6 (0.46) XDHCA1CA2CA4CA6
SCHEMBL4750717 0.80 KDM4E (0.63) XDHCA1CA2CA4CA6
SCHEMBL13725253 0.80 ALDH1A1 (0.46) XDHCA1CA2CA4CA6
SCHEMBL14262449 0.80 XDH (0.44) XDHCA1CA2CA4CA6
SCHEMBL15541448 0.80 XDH (0.44) XDHCA1CA2CA4CA6
SCHEMBL3934805 0.80 CA2 (0.58) XDHCA1CA2ALOX15IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 487 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120059220-A Gelatin polymer molecular brush, surface treatment liquid and application thereof 深圳市松柏科工股份有限公司 2025-05-30 CN claimed
CN-119985745-A Detection method for micromolecular phenolic substances and application thereof 北京中医药大学 2025-05-13 CN claimed
CN-119570825-A Method for efficiently synthesizing protoberberine compounds and application thereof 中国科学院分子植物科学卓越创新中心 2025-03-07 CN claimed
CN-112410379-B Microorganisms producing benzylisoquinoline alkaloid (BIA) precursors and methods of making and using the precursors 小利兰·斯坦福大学托管委员会 2024-12-31 CN claimed
US-20240209403-A1 METHODS OF PRODUCING MORPHINAN ALKALOIDS AND DERIVATIVES HERCULES CAPITAL, INC., AS AGENT 2024-06-27 US claimed
US-12018304-B2 Benzylisoquinoline alkaloid (BIA) precursor producing microbes, and methods of making and using the same THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-06-25 US claimed
CN-117947071-A Synthetic route of reticuline and application thereof 中国科学院分子植物科学卓越创新中心 2024-04-30 CN claimed
EP-4076733-B1 PEROVSKITE SOLAR CELL PROVIDED WITH AN ADSORBENT MATERIAL FOR ADSORBING TOXIC MATERIALS ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2024-02-07 EP claimed
CN-117487360-A Organic silicon rubber and preparation method and application thereof 湖南贝森新材料有限公司 2024-02-02 CN claimed
US-11884949-B2 Methods of producing morphinan alkaloids and derivatives ANTHEIA, INC. (US) 2024-01-30 US claimed
US-20070270332-A1 METHODS AND ASSAYS USEFUL IN THE TREATMENT OF ALCOHOL DEPENDENCE OR ALCOHOL ABUSE VALLEE BERT L 2007-11-22 US claimed
EP-1077697-B1 METHODS AND ASSAYS USEFUL IN THE TREATMENT OF ALCOHOL DEPENDENCE OR ALCOHOL ABUSE ENDOWMENT FOR RES IN HUMAN BIO (US) 2006-07-19 EP claimed
EP-1645272-A2 Daidzin derivatives for the treatment of alcohol dependence or alcohol abuse THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) 2006-04-12 EP claimed
EP-1542675-A1 COMPOUNDS USEFUL FOR THE INHIBITION OF ALDH The Endowment For Research In Human Biology, Inc. (US) 2005-06-22 EP claimed
US-20040068003-A1 Compounds useful for the inhibition of ALDH THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC, 2004-04-08 US claimed
WO-2004002470-A1 COMPOUNDS USEFUL FOR THE INHIBITION OF ALDH THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) 2004-01-08 WO claimed
US-20030175259-A1 Use of corneal hardening agents in enzymeorthokeratology KARAGEOZIAN HAMPER (US) 2003-09-18 US claimed
EP-1077697-A1 METHODS AND ASSAYS USEFUL IN THE TREATMENT OF ALCOHOL DEPENDENCE OR ALCOHOL ABUSE THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) 2001-02-28 EP claimed
WO-1999058124-A1 METHODS AND ASSAYS USEFUL IN THE TREATMENT OF ALCOHOL DEPENDENCE OR ALCOHOL ABUSE THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) 1999-11-18 WO claimed
WO-1999036088-A1 RECOMBINANT CtB-BASED VACCINES MAXIM PHARMACEUTICALS, INC. (US) 1999-07-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070270332-A1 METHODS AND ASSAYS USEFUL IN THE TREATMENT OF ALCOHOL DEPENDENCE OR ALCOHOL ABUSE ADH1A, ADH5, ADH1C XDH 8/4885CA1 637/4885CA2 2931/4885
US-20040068003-A1 Compounds useful for the inhibition of ALDH ALDH2, ALDH1A1, ALDH3A1 XDH 108/4885CA1 864/4885CA2 947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.