Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26619663 | 0.86 | DPP4 (0.35) | — | |
| SCHEMBL24995531 | 0.80 | HSD11B1 (0.31) | HSD11B1 | |
| SCHEMBL24317422 | 0.80 | IRAK4 (0.32) | HSD11B1 | |
| SCHEMBL26632667 | 0.79 | DPP4 (0.32) | — | |
| SCHEMBL26823952 | 0.78 | HRH3 (0.34) | — | |
| SCHEMBL24317421 | 0.77 | — | — | |
| SCHEMBL27010152 | 0.77 | DPP4 (0.33) | — | |
| SCHEMBL8444083 | 0.74 | DPP4 (0.37) | — | |
| SCHEMBL24317423 | 0.74 | DPP4 (0.33) | — | |
| SCHEMBL12409015 | 0.73 | HRH3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081925-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| US-9585884-B2 | Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2017-03-07 | — | — | US | disclosed |