SCHEMBL26619663

SCHEMBL26619663

COC1CCCC(N2CC(OC)C2)C1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.35
DPP7 Q9UHL4 1/20 0.35
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26632667 0.89 DPP4 (0.32) DPP4DPP7HRH3
SCHEMBL26823952 0.87 HRH3 (0.34) HRH3
SCHEMBL24317423 0.86 DPP4 (0.33) DPP4DPP7
SCHEMBL27010152 0.86 DPP4 (0.33) DPP4DPP7
SCHEMBL24317421 0.86
SCHEMBL24315775 0.86 HSD11B1 (0.31)
SCHEMBL26619643 0.83 DPP4 (0.38) DPP4DPP7HRH3
SCHEMBL12409015 0.82 HRH3 (0.34) DPP4HRH3
SCHEMBL17665915 0.80 HRH3 (0.36) DPP4HRH3
SCHEMBL26619777 0.79 SIGMAR1 (0.41) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2023-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 IKZF1, IKZF3, IKZF2 DPP4 2502/4885DPP7 3251/4885HRH3 4242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.