Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19288300 | 0.85 | GRM5 (0.39) | TAAR1ESR2IDO1NFE2L2 | |
| SCHEMBL5777460 | 0.84 | TAAR1 (0.47) | TAAR1ESR2CDC7ROCK2MAP4K4 | |
| SCHEMBL24315367 | 0.83 | TDO2 (0.40) | TAAR1ESR2HTR1AHTR7IDO1 | |
| SCHEMBL24315982 | 0.82 | BACE1 (0.39) | MEN1KMT2AALDH1A1HPGDFFAR1 | |
| SCHEMBL20898099 | 0.78 | MEN1 (0.46) | TAAR1ESR2CDC7ROCK2MAP4K4 | |
| SCHEMBL31067143 | 0.78 | MEN1 (0.46) | TAAR1ESR2CDC7ROCK2MAP4K4 | |
| SCHEMBL21770978 | 0.77 | TAAR1 (0.60) | TAAR1ESR2CDC7ROCK2MAP4K4 | |
| SCHEMBL780417 | 0.75 | PTPRC (0.50) | TAAR1ESR2CDC7ROCK2MAP4K4 | |
| SCHEMBL30525640 | 0.75 | PTPRC (0.50) | TAAR1ESR2CDC7ROCK2MAP4K4 | |
| SCHEMBL24315321 | 0.75 | ADORA1 (0.41) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3619196-B1 | 2-{[2-(PHENYLOXYMETHYL)PYRIDIN-5-YL]OXY}-ETHANAMIN-DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES E.G. FOR CROP PROTECTION | BAYER CROPSCIENCE AG (DE) | 2022-03-30 | — | — | EP | disclosed |
| US-9585884-B2 | Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2017-03-07 | — | — | US | disclosed |