Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316004 | 0.83 | TAAR1 (0.41) | TAAR1MEN1KMT2ANOTUMESR2 | |
| SCHEMBL24316016 | 0.83 | TDO2 (0.41) | TDO2DHFRALOX5MAOBTAAR1 | |
| SCHEMBL14685847 | 0.81 | GABRP (0.45) | TDO2DHFRALOX5MAOBTAAR1 | |
| SCHEMBL24315982 | 0.80 | BACE1 (0.39) | ALOX5MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3835519 | 0.79 | PTPRC (0.47) | TDO2DHFRALOX5MAOBTAAR1 | |
| SCHEMBL21770966 | 0.78 | ALDH1A1 (0.52) | TDO2DHFRALOX5MAOBTAAR1 | |
| SCHEMBL26805949 | 0.78 | ESR2 (0.43) | TDO2DHFRALOX5MAOBESR2 | |
| SCHEMBL19288300 | 0.76 | GRM5 (0.39) | TDO2TAAR1ESR2IDO1 | |
| SCHEMBL16290533 | 0.74 | CYP1A1 (0.49) | MAOBKMT2ANOTUMRELA | |
| SCHEMBL10064798 | 0.74 | AKR1C3 (0.39) | TDO2DHFRALOX5MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3619196-B1 | 2-{[2-(PHENYLOXYMETHYL)PYRIDIN-5-YL]OXY}-ETHANAMIN-DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES E.G. FOR CROP PROTECTION | BAYER CROPSCIENCE AG (DE) | 2022-03-30 | — | — | EP | disclosed |