Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RORB | Q92753 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3269842 | 0.84 | TDO2 (0.46) | TDO2ALOX5DHFRTAAR1NUDT1 | |
| SCHEMBL24315367 | 0.83 | TDO2 (0.40) | TDO2ALOX5DHFRTAAR1NUDT1 | |
| SCHEMBL10551642 | 0.82 | CYP2A6 (0.54) | ALOX5MEN1KMT2AESR2SMN1; SMN2 | |
| SCHEMBL21770705 | 0.77 | ALDH1A1 (0.54) | TDO2ALOX5DHFRTAAR1MEN1 | |
| SCHEMBL4450500 | 0.75 | AHR (0.58) | TDO2ALOX5DHFRTAAR1NUDT1 | |
| SCHEMBL29554995 | 0.75 | AHR (0.58) | TDO2ALOX5DHFRTAAR1NUDT1 | |
| SCHEMBL1520883 | 0.75 | CYP2A6 (0.62) | TDO2ALOX5DHFRTAAR1MEN1 | |
| SCHEMBL29464821 | 0.75 | CYP2A6 (0.62) | TDO2ALOX5DHFRTAAR1MEN1 | |
| SCHEMBL24315446 | 0.74 | PRMT5 (0.44) | ADORA2AADORA1 | |
| SCHEMBL16290690 | 0.73 | CYP1A1 (0.50) | KMT2ARORBNOTUMRELAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3619196-B1 | 2-{[2-(PHENYLOXYMETHYL)PYRIDIN-5-YL]OXY}-ETHANAMIN-DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES E.G. FOR CROP PROTECTION | BAYER CROPSCIENCE AG (DE) | 2022-03-30 | — | — | EP | disclosed |
| US-9585884-B2 | Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2017-03-07 | — | — | US | disclosed |