Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316556 | 0.90 | KDM4E (0.41) | KDM4EGLAGAATHRBPIK3CA | |
| SCHEMBL29539198 | 0.90 | KDM4E (0.41) | KDM4EGLAGAATHRBPIK3CA | |
| SCHEMBL24316808 | 0.88 | POLB (0.41) | KDM4EGLAGAATHRBPIK3CA | |
| SCHEMBL24316797 | 0.77 | KDM4E (0.38) | KDM4EGLAGAAPIK3CAMTOR | |
| SCHEMBL24316440 | 0.77 | CSF1R (0.38) | PIK3CAMTOR | |
| SCHEMBL29539062 | 0.74 | KDM4E (0.36) | KDM4EGLAGAATHRBPIK3CA | |
| SCHEMBL24316434 | 0.73 | CSF1R (0.53) | KDM4EPIK3CAMTORPOLBRXFP1 | |
| SCHEMBL24316624 | 0.73 | KDM4E (0.36) | KDM4EGLAGAATHRBPIK3CA | |
| SCHEMBL24316983 | 0.73 | CSF1R (0.46) | PIK3CAMTORRXFP1GRM5ALDH1A1 | |
| SCHEMBL24316982 | 0.73 | CSF1R (0.48) | KDM4EGLAGAAPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |