Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.38 |
| ▸ | MTOR | P42345 | 3/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316434 | 0.93 | CSF1R (0.53) | CSF1RPIK3CAMTORALDH1A1GRM5 | |
| SCHEMBL24316982 | 0.92 | CSF1R (0.48) | CSF1RPIK3CAMTORALDH1A1GRM5 | |
| SCHEMBL24316814 | 0.91 | CSF1R (0.47) | CSF1RPIK3CAMTORALDH1A1GRM5 | |
| SCHEMBL24316622 | 0.91 | CYP11B1 (0.39) | CSF1RPIK3CAMTORMCHR1RXFP1 | |
| SCHEMBL24316551 | 0.90 | GRM5 (0.49) | CSF1RGRM5ALKBH1 | |
| SCHEMBL24316448 | 0.89 | CSF1R (0.45) | CSF1RPIK3CAMTORGRM5MCHR1 | |
| SCHEMBL24316437 | 0.88 | CSF1R (0.45) | CSF1RPIK3CAMTORGRM5RXFP1 | |
| SCHEMBL24316587 | 0.87 | CSF1R (0.44) | CSF1RPIK3CAMTORMCHR1RXFP1 | |
| SCHEMBL24316553 | 0.87 | CSF1R (0.46) | CSF1RPIK3CAMTORRXFP1ALKBH1 | |
| SCHEMBL24316621 | 0.86 | PIK3CA (0.38) | CSF1RPIK3CAMTORALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |