SCHEMBL24316938

SCHEMBL24316938

OC1(c2cc3ccccc3cc2-c2cccc(Cl)c2)C2CC3CC(C2)C1C3

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.39
CXCR3 P49682 3/20 0.36
HCRTR1 O43613 3/20 0.33
HCRTR2 O43614 3/20 0.33
HSD11B1 P28845 2/20 0.33
ADORA1 P30542 1/20 0.33
CHRM1 P11229 5/20 0.32
CHRM3 P20309 4/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
MIF P14174 1/20 0.31
GRM5 P41594 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24316331 0.88 PDK2 (0.40) PDK2CXCR3HSD11B1ADORA1CHRM1
SCHEMBL24316335 0.83 HSD11B1 (0.33) PDK2CXCR3HSD11B1KDM4ENPC1
SCHEMBL25035892 0.80 PDK2 (0.35) PDK2CXCR3HCRTR1HCRTR2HSD11B1
SCHEMBL23606148 0.78 PDK2 (0.48) PDK2HSD11B1CHRM1CHRM3KDM4E
SCHEMBL25054827 0.78 PDK2 (0.48) PDK2HSD11B1CHRM1CHRM3KDM4E
SCHEMBL25038269 0.77 CYP2A6 (0.40) PDK2HSD11B1
SCHEMBL24316343 0.75 SLC6A3 (0.40) PDK2HSD11B1KDM4ENPC1ALDH1A1
SCHEMBL24618564 0.75 PDK2 (0.43) PDK2CXCR3HSD11B1ALDH1A1LMNA
SCHEMBL24316404 0.75 KMT2A (0.37) PDK2HSD11B1CHRM1KDM4ENPC1
SCHEMBL24316388 0.73 CYP1A2 (0.40) PDK2CXCR3HSD11B1ADORA1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022068292-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME 陕西莱特光电材料股份有限公司 2022-04-07 WO disclosed