Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 4/20 | 0.38 |
| ▸ | XDH | P47989 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316988 | 0.85 | CHRM4 (0.41) | DHODHCSF1RNPC1RAB9ALMNA | |
| SCHEMBL21327653 | 0.79 | CSF1R (0.54) | CSF1RNPC1RAB9ALMNA | |
| SCHEMBL24316420 | 0.79 | MAOB (0.45) | CSF1RNPC1RAB9ALMNASCN9A | |
| SCHEMBL24316985 | 0.78 | MRGPRX4 (0.49) | CSF1RNPC1RAB9ALMNASCN9A | |
| SCHEMBL24316419 | 0.77 | PDGFRB (0.49) | NPC1RAB9ALMNA | |
| SCHEMBL24316418 | 0.73 | CSF1R (0.41) | CSF1R | |
| SCHEMBL19461724 | 0.70 | CSF1R (0.46) | CSF1RNPC1RAB9ALMNA | |
| SCHEMBL24316415 | 0.69 | CNR1 (0.47) | CSF1RNPC1RAB9A | |
| SCHEMBL24316986 | 0.69 | KDM4E (0.50) | LMNA | |
| SCHEMBL17106561 | 0.69 | NPC1 (0.49) | NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |