SCHEMBL24317039

SCHEMBL24317039

Brc1cccc(-c2cccc(-c3ccc4c(Br)cccc4c3)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BIRC5 O15392 1/20 0.47
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
HSD17B1 P14061 7/20 0.42
HSD17B2 P37059 7/20 0.42
MAOB P27338 2/20 0.41
MAOA P21397 1/20 0.41
SLC9A1 P19634 1/20 0.40
ALDH1A1 P00352 3/20 0.39
RAB9A P51151 2/20 0.39
CYP1A2 P05177 2/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
KMT2A Q03164 1/20 0.39
HPGD P15428 2/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
MAPT P10636 1/20 0.38
HK1 P19367 1/20 0.38
HKDC1 Q2TB90 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20033090 0.85 HSD17B1 (0.49) ESR1ESR2HSD17B1HSD17B2SLC9A1
SCHEMBL1527443 0.81 BIRC5 (0.51) BIRC5ESR1ESR2HSD17B1HSD17B2
SCHEMBL30366175 0.80 CYP2A6 (0.52) MAOASLC9A1ALDH1A1CYP1A2MEN1
SCHEMBL29656897 0.80 CYP2A6 (0.52) MAOASLC9A1ALDH1A1CYP1A2MEN1
SCHEMBL1461517 0.80 CYP2A6 (0.52) MAOASLC9A1ALDH1A1CYP1A2MEN1
SCHEMBL1527474 0.77 BIRC5 (0.47) BIRC5ESR1ESR2HSD17B1HSD17B2
SCHEMBL15197469 0.77 CYP2A6 (0.56) BIRC5ESR1ESR2HSD17B1HSD17B2
SCHEMBL15624388 0.77 ALDH1A1 (0.50) BIRC5MAOBMAOAALDH1A1RAB9A
SCHEMBL29398919 0.77 ALDH1A1 (0.50) BIRC5MAOBMAOAALDH1A1RAB9A
SCHEMBL191276 0.77 ALDH1A1 (0.50) BIRC5MAOBMAOAALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022068292-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME 陕西莱特光电材料股份有限公司 2022-04-07 WO disclosed