Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MPI | P34949 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418165 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1GAAHPGDMPI | |
| SCHEMBL5636442 | 0.84 | KDM4E (0.46) | KDM4EALDH1A1GAAHPGDMPI | |
| SCHEMBL1691510 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1GAAHPGDMPI | |
| SCHEMBL15332136 | 0.80 | ATM (0.46) | KDM4EALDH1A1GAAHPGDMPI | |
| SCHEMBL19428324 | 0.79 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDMPI | |
| SCHEMBL11227014 | 0.77 | ATM (0.44) | KDM4EALDH1A1GAAHPGDMPI | |
| SCHEMBL2755241 | 0.74 | MEN1 (0.51) | KDM4EALDH1A1GAAHPGDMPI | |
| SCHEMBL672108 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1GAAHPGDMPI | |
| SCHEMBL27876872 | 0.74 | KDM4E (0.48) | KDM4EALDH1A1GAAHPGDMPI | |
| SCHEMBL197522 | 0.72 | CA1 (0.79) | KDM4EALDH1A1GAATDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251042-A1 | TOTAL SYNTHESIS OF PIRFENIDONE | Suzhou Fude Zhaofeng Biochemical Technology Co., Ltd (CN) | 2022-08-11 | — | — | US | disclosed |
| WO-2022052391-A1 | METHOD FOR SYNTHESIZING VORTIOXETINE | 苏州富德兆丰生化科技有限公司 | 2022-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220251042-A1 | TOTAL SYNTHESIS OF PIRFENIDONE | PIR, CYP2B6, CYP26B1 | KDM4E 386/4885ALDH1A1 50/4885GAA 4120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.