Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18758173 | 0.98 | XDH (0.50) | KDM4EALDH1A1GAAHPGDMPI | |
| SCHEMBL9462506 | 0.86 | APP (0.50) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2028396 | 0.83 | ADH5 (0.32) | — | |
| SCHEMBL6961694 | 0.83 | ABL1 (0.51) | KDM4EALDH1A1XDHMAPTNPC1 | |
| SCHEMBL13545637 | 0.82 | MAPT (0.61) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL13411813 | 0.81 | ADH5 (0.36) | — | |
| SCHEMBL1458176 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDTDP1MAPT | |
| SCHEMBL702808 | 0.80 | ALDH1A1 (0.53) | KDM4EALDH1A1GAAHPGDMPI | |
| SCHEMBL18383408 | 0.80 | CYP2C9 (0.45) | ALDH1A1GAAHPGDTDP1MAPT | |
| SCHEMBL12896131 | 0.80 | NOTUM (0.45) | XDHMAPTTP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724673-B2 | Supported alkoxylated organotin reactant, preparation and use for heterogeneous-phase synthesis of tetrazoles | UNIVERSITE DE NANTES (FR) | 2017-08-08 | — | — | US | claimed |
| EP-2726515-B1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | CENTRE NAT RECH SCIENT (FR) | 2015-04-01 | — | — | EP | claimed |
| US-20140206825-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-24 | — | — | US | claimed |
| EP-2726515-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | Centre National De La Recherche Scientifique (FR) | 2014-05-07 | — | — | EP | claimed |
| WO-2013001235-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-01-03 | — | — | WO | claimed |
| US-6576414-B1 | PKsp of said first organic silver salt is at least 0.5 lower than the pKsp of said second silver salt; high speed, storage stable | EASTMAN KODAK COMPANY | 2003-06-10 | — | — | US | claimed |
| US-6548236-B1 | The dye-providing couplers in the multilayers being different in hue, forming at least three dye images of different visible or non-visible colors | EASTMAN KODAK COMPANY | 2003-04-15 | — | — | US | claimed |
| US-6426181-B2 | THE SECOND SILVER SALT IS A THERMAL FOG INHIBITOR THAT PREVENTS DESORPTION OF SENSITIZING DYES FROM THE IMAGING SILVER HALIDE GRAINS AND IS PREFERABLY A MERCAPTO-HETEROCYCLIC COMPOUND | EASTMAN KODAK COMPANY | 2002-07-30 | — | — | US | claimed |
| US-20020015928-A1 | Mixtures of organic silver salts in color photothermographic systems | IRVING LYN M (US) | 2002-02-07 | — | — | US | claimed |
| EP-3138840-B1 | THIADIAZOLIDINE DERIVATIVE AS ANTI-ENTEROVIRUS 71 | JIANGSU KANION PHARMACEUTICAL CO LTD (CN) | 2020-09-23 | — | — | EP | disclosed |
| CN-109503505-B | Synthesis method of 5-substituted tetrazole compound | 浙江工业大学 | 2020-07-21 | — | — | CN | disclosed |
| US-10577327-B2 | Pyridine based ionic fluoride for catalyzing indole and tetrazole formation | KING ABDULAZIZ UNIVERSITY (SA) | 2020-03-03 | — | — | US | disclosed |
| US-10577327-B2 | Pyridine based ionic fluoride for catalyzing indole and tetrazole formation | KING ABDULAZIZ UNIVERSITY (SA) | 2020-03-03 | — | — | US | disclosed |
| CN-106661009-B | Anti- enteric virus71 thiadiazolidine derivative | 江苏康缘药业股份有限公司 | 2019-11-26 | — | — | CN | disclosed |
| EP-0388967-A1 | Aldose reductase inhibitor | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1990-09-26 | — | — | EP | disclosed |
| US-4647572-A | Iodoallyl and iodopropargyl substituted tetrazoles and anti-microbial compositions thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 1987-03-03 | — | — | US | disclosed |
| EP-0039892-B1 | SUBSTITUTED PHENYL ETHERS | CIBA-GEIGY AG (CH) | 1986-12-30 | — | — | EP | disclosed |
| US-4559354-A | ADRENERGIC BLOCKING AGENTS AND STIMULANTS; CARDIOTONIC, ANTIARRHYTHMIA AND INOTROPIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |
| EP-0107859-A1 | Tetrazole compounds, process for preparing the same and antibacterial and antifungal compositions containing the same as active ingredient | MEIJI SEIKA KAISHA LTD. (JP) | 1984-05-09 | — | — | EP | disclosed |
| EP-0039892-A1 | Substituted phenyl ethers | CIBA-GEIGY AG (CH) | 1981-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577327-B2 | Pyridine based ionic fluoride for catalyzing indole and tetrazole formation | FLI1, ABL1, INMT | KDM4E 2056/4885ALDH1A1 1278/4885GAA 4236/4885 |
| US-20140206825-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | ALK, TST, TEKT1 | KDM4E 3246/4885ALDH1A1 861/4885GAA 3403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.