Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 6/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690369 | 0.77 | DRD3 (0.42) | PGRDRD3 | |
| SCHEMBL13939978 | 0.76 | SIGMAR1 (0.41) | PGRSLC6A2NCF1DRD3HTR2A | |
| SCHEMBL24316246 | 0.75 | PGR (0.39) | PGRSLC6A2NCF1DRD3HTR2A | |
| SCHEMBL19148902 | 0.72 | ADH1A (0.45) | — | |
| SCHEMBL19150951 | 0.71 | ADH1A (0.47) | — | |
| SCHEMBL19226484 | 0.69 | PGR (0.43) | PGRSLC6A2BCHEHTR2AHTR2C | |
| SCHEMBL18820340 | 0.69 | PGR (0.39) | PGRSLC6A2NCF1HTR2AHTR2C | |
| SCHEMBL81626 | 0.69 | PGR (0.39) | PGRSLC6A2NCF1HTR2AHTR2C | |
| SCHEMBL18820341 | 0.69 | PGR (0.39) | PGRSLC6A2NCF1HTR2AHTR2C | |
| SCHEMBL688629 | 0.69 | DRD3 (0.45) | DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081927-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |