SCHEMBL24317733

SCHEMBL24317733

c1cc2c3c(cccc3c#1)CN(Cc1cccc(CN3Cc4cccc5cccc(c45)C3)c1)C2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.35
NCF1 P14598 1/20 0.33
SIGMAR1 Q99720 2/20 0.33
KMT2A Q03164 2/20 0.32
HRH4 Q9H3N8 1/20 0.32
DRD2 P14416 1/20 0.32
DRD3 P35462 1/20 0.32
KCNH2 Q12809 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
DRD4 P21917 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2C P28335 1/20 0.30
SLC6A4 P31645 1/20 0.30
OPRK1 P41145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21082344 0.96 HRH4 (0.32) PRMT6HRH4
SCHEMBL17618298 0.83 SIGMAR1 (0.43) PRMT6NCF1SIGMAR1KMT2AHRH4
SCHEMBL17618299 0.79 HRH4 (0.40) PRMT6NCF1SIGMAR1KMT2AHRH4
SCHEMBL17618297 0.70 SIGMAR1 (0.49) PRMT6NCF1SIGMAR1DRD2DRD3
SCHEMBL31440214 0.65 KMT2A (0.42) SIGMAR1KMT2ADRD2KCNH2MEN1
SCHEMBL24317721 0.65 TMEM97 (0.49) SIGMAR1KMT2AHRH4DRD2DRD3
SCHEMBL21082369 0.64 ACHE (0.35) PRMT6
SCHEMBL17618296 0.63 SIGMAR1 (0.46) SIGMAR1KMT2ADRD3KCNH2MEN1
SCHEMBL8391771 0.62 CYP3A4 (0.41) HRH4HTR2C
SCHEMBL20457589 0.60 ACHE (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220073699-A1 OXYGEN SCAVENGERS, COMPOSITIONS COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT 2022-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220073699-A1 OXYGEN SCAVENGERS, COMPOSITIONS COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS PRDX5, LPO, CAT PRMT6 3319/4885NCF1 293/4885SIGMAR1 130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.