Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 9/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796113 | 0.83 | GAA (0.56) | GPR84HTR2AGAAHTR2CHTR2B | |
| SCHEMBL29940979 | 0.83 | GAA (0.56) | GPR84HTR2AGAAHTR2CHTR2B | |
| SCHEMBL9004442 | 0.80 | GPR84 (0.59) | GPR84FFAR1HTR2AGAAHTR2C | |
| SCHEMBL10262953 | 0.75 | GPR84 (0.58) | GPR84FFAR1HTR2AGAAHTR2C | |
| SCHEMBL21026823 | 0.75 | IDO1 (0.56) | GPR84FFAR1HTR1DGAAMEN1 | |
| SCHEMBL29952017 | 0.72 | CYP2A6 (0.60) | GPR84FFAR1HTR1DHTR2AHTR1A | |
| SCHEMBL25075602 | 0.72 | GPR84 (0.42) | GPR84FFAR1HTR2AGAAHTR2C | |
| SCHEMBL10615515 | 0.72 | HTR2A (0.62) | GPR84FFAR1HTR1DHTR2AHTR2C | |
| SCHEMBL11611366 | 0.72 | CLK1 (0.43) | GAAMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL29926495 | 0.71 | IMPDH2 (0.47) | GPR84FFAR1HTR1DHTR2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081927-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |