Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796113 | 1.00 | GAA (0.56) | GAAALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL24317844 | 0.83 | GPR84 (0.42) | GAAALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL19872766 | 0.77 | GPR17 (0.50) | GAAALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL1146046 | 0.76 | CYP2C9 (0.56) | GAAALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL6287959 | 0.74 | ALDH1A1 (0.69) | GAAALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL16302212 | 0.73 | GAA (0.64) | GAAALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL25192370 | 0.73 | HTR2A (0.64) | GAAALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL2403442 | 0.73 | ALDH1A1 (0.68) | GAAALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL4386307 | 0.72 | TUBB4A (0.54) | GAAALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL261971 | 0.72 | ALDH1A1 (0.55) | GAAALDH1A1KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942478-B | Synthetic method of 3-methylthio indole derivative | 南京理工大学 | 2022-07-22 | — | — | CN | disclosed |