Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24318168 | 0.83 | ALDH1A1 (0.44) | HPGDNPSR1RAB9AGAAMEN1 | |
| SCHEMBL19626178 | 0.83 | CXCR2 (0.47) | HPGDNPSR1NPC1RAB9AGAA | |
| SCHEMBL8962199 | 0.76 | TDP1 (0.50) | HPGDNPC1RAB9AGAAMEN1 | |
| SCHEMBL429859 | 0.74 | GAA (0.62) | HPGDNPSR1NPC1RAB9AGAA | |
| SCHEMBL29473561 | 0.74 | GAA (0.62) | HPGDNPSR1NPC1RAB9AGAA | |
| SCHEMBL8691617 | 0.74 | RAPGEF4 (0.57) | HPGDNPSR1NPC1RAB9AGAA | |
| SCHEMBL1029810 | 0.74 | ALDH1A1 (0.51) | HPGDNPSR1GAAMEN1KMT2A | |
| SCHEMBL30514613 | 0.74 | HPGD (0.67) | HPGDNPSR1NPC1RAB9AGAA | |
| SCHEMBL9461706 | 0.73 | HPGD (1.00) | HPGDNPSR1NPC1RAB9AGAA | |
| SCHEMBL24137168 | 0.73 | HPGD (1.00) | HPGDNPSR1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022048565-A1 | PREPARATION METHOD FOR ASYMMETRIC DIARYL SUBSTITUTED P-PHENYLENEDIAMINE COMPOUND | 圣奥化学科技有限公司 | 2022-03-10 | — | — | WO | disclosed |