SCHEMBL8962199

SCHEMBL8962199

CC(C)(C)c1ccccc1Nc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.50
MAPT P10636 4/20 0.50
GAA P10253 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 2/20 0.50
RECQL P46063 2/20 0.50
GLA P06280 1/20 0.50
ALDH1A1 P00352 8/20 0.48
LMNA P02545 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
HSD17B10 Q99714 4/20 0.46
ALOX15 P16050 4/20 0.45
TSHR P16473 4/20 0.45
CYP3A4 P08684 2/20 0.45
ATM Q13315 2/20 0.45
HPGD P15428 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28793668 0.88 PTGER4 (0.42) TDP1MAPTGAAMEN1KMT2A
SCHEMBL29499693 0.86 ALDH1A1 (0.48) TDP1MAPTGAAMEN1KMT2A
SCHEMBL2818765 0.86 ALDH1A1 (0.48) TDP1MAPTGAAMEN1KMT2A
SCHEMBL9703296 0.86 P2RY1 (0.42) TDP1MAPTGAAKDM4EGLA
SCHEMBL28698942 0.84 MAPT (0.58) TDP1MAPTGAAMEN1KMT2A
SCHEMBL21446576 0.84 MAPT (0.48) TDP1MAPTGAAMEN1KMT2A
SCHEMBL32661321 0.84 MAPT (0.48) TDP1MAPTGAAMEN1KMT2A
SCHEMBL31916 0.83 MAPT (0.47) TDP1MAPTGAAMEN1KMT2A
SCHEMBL25502785 0.81 GAA (0.42) TDP1MAPTGAAMEN1KMT2A
SCHEMBL22169081 0.81 ALDH1A1 (0.50) TDP1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023136476-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2023-07-20 WO disclosed
US-20200377513-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2020-12-03 US disclosed
EP-0512950-B1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA GEIGY AG (CH) 1996-01-17 EP disclosed
US-5244953-A Polymers, oxidation and heat resistance CIBA-GEIGY CORPORATION (US) 1993-09-14 US disclosed
EP-0512950-A1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA-GEIGY AG (CH) 1992-11-11 EP disclosed
US-5160647-A High temperature lubricants, heat and oxidation resistance CIBA-GEIGY CORPORATION (US) 1992-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200377513-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE PIEZO1, TMEM109, LEF1 TDP1 3717/4885MAPT 2589/4885GAA 1301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.