Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SGPL1 | O95470 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | PDXK | O00764 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14646864 | 0.89 | LMNA (0.56) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11625665 | 0.79 | NOS1 (0.36) | SGPL1NOS1NR5A1ESR1PTGS1 | |
| SCHEMBL11622427 | 0.79 | ESR1 (0.57) | KDM4EALDH1A1HPGDLMNASGPL1 | |
| SCHEMBL11625885 | 0.79 | PLA2G2A (0.40) | NOS1ESR1MEN1KMT2A | |
| SCHEMBL17119505 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1LMNANOS1NR5A1 | |
| SCHEMBL21916476 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL13498731 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL3442482 | 0.73 | HPGD (0.79) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL13176882 | 0.72 | ESR1 (0.64) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL14646865 | 0.72 | LMNA (0.64) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081777-A1 | METHOD OF PREVENTING KIDNEY INJURY DISRUPTION OF INTESTINAL LYMPHATICS | VANDERBILT UNIVERSITY (US) | 2022-04-21 | — | — | WO | disclosed |