SCHEMBL2432048

SCHEMBL2432048

Cc1cc(C)c2cccc(O)c2n1.Cc1cc(C)c2cccc(O)c2n1.Oc1ccc(-c2ccccc2)cc1.[Al]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
CYP1A2 P05177 2/20 0.45
TNKS O95271 4/20 0.44
PARP1 P09874 4/20 0.44
TNKS2 Q9H2K2 4/20 0.44
KMT2A Q03164 5/20 0.43
ESR1 P03372 4/20 0.43
ESR2 Q92731 3/20 0.43
OPRK1 P41145 1/20 0.43
CCR6 P51684 1/20 0.43
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
MMP3 P08254 1/20 0.42
BCL2L1 Q07817 1/20 0.42
MEN1 O00255 4/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
METAP2 P50579 1/20 0.41
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2430328 0.90 HSD17B2 (0.48) KDM4ETDP1CYP1A2TNKSPARP1
SCHEMBL28845595 0.89 HSD17B2 (0.49) KDM4ETDP1CYP1A2TNKSPARP1
SCHEMBL29966202 0.87 KDM4E (0.61) KDM4ETDP1CYP1A2TNKSPARP1
2-Phenylphenol SCHEMBL2437644 0.86 KDM4E (0.48) KDM4ETDP1CYP1A2TNKSPARP1
SCHEMBL30587187 0.85 KDM4E (0.62) KDM4ETDP1CYP1A2TNKSPARP1
SCHEMBL4299350 0.85 KDM4E (0.62) KDM4ETDP1CYP1A2TNKSPARP1
SCHEMBL2873413 0.85 KDM4E (0.62) KDM4ETDP1CYP1A2TNKSPARP1
SCHEMBL4302340 0.83 KDM4E (0.61) KDM4ETDP1CYP1A2TNKSPARP1
SCHEMBL27551420 0.83 KDM4E (0.61) KDM4ETDP1CYP1A2TNKSPARP1
SCHEMBL4298175 0.83 KDM4E (0.61) KDM4ETDP1CYP1A2TNKSPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190214575-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC CORPORATION (JP) 2019-07-11 US disclosed
US-9590182-B2 Benzofluorene compound, material for luminescent layer using said compound and organic electroluminescent device JNC CORPORATION (JP) 2017-03-07 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
EP-2897184-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC Corporation (JP) 2015-07-22 EP disclosed
US-20150097162-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC CORPORATION (JP) 2015-04-09 US disclosed
US-20140319510-A1 BENZOFLUORENE COMPOUND, MATERIAL FOR LUMINESCENT LAYER USING SAID COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE JNC CORPORATION (JP) 2014-10-30 US disclosed
EP-2784057-A1 BENZOFLUORENE COMPOUND, MATERIAL FOR LUMINESCENT LAYER USING SAID COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE JNC Corporation (JP) 2014-10-01 EP disclosed
EP-1935919-B1 POLYMER CONTAINING SULFO GROUP AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE POLYMER YAMAMOTO CHEMICALS INC (JP) 2012-09-05 EP disclosed
US-8012608-B2 Polymer containing sulfo group and organic electroluminescent element containing the polymer Yamamoto Chemcials, Inc. (JP) 2011-09-06 US disclosed
US-20090230851-A1 Polymer Containing Sulfo Group and Organic Electroluminescent Element Containing the Polymer MITSUI CHEMICALS, INC. (JP) 2009-09-17 US disclosed
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device JNC CORPORATION (JP) 2008-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device LEF1, TRPA1, BRD8 KDM4E 1083/4885TDP1 2553/4885CYP1A2 393/4885
US-20190214575-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE L1CAM, VDAC1, VDAC2 KDM4E 1253/4885TDP1 3863/4885CYP1A2 2204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.